Range limit to
486 cohorts selected out of 486 total, 829 median lifespan -
StrainSexTreatmentDosageTemperaturePer dwell.Start ageStudyLifespanYearSite
UM-HET3maleINT-767 FXR/TGR5 agonist180 ppm300 daysPMID 30688027 2019med 900 max 12192012University of Michigan at Ann Arbor
UM-HET3femaleAcarbose1000 ppm480 daysPMID 27312235 2016med 919 max 12432012University of Texas Health Science Center
UM-HET3femaleControl PMID 30688027 2019med 877 max 12552012University of Texas Health Science Center
UM-HET3female2-(2-Hydroxyphenyl)benzoxazole1 ppm450 daysPMID 30688027 2019med 852 max 12262012University of Texas Health Science Center
UM-HET3femaleINT-767 FXR/TGR5 agonist180 ppm300 daysPMID 30688027 2019med 856 max 11722012University of Texas Health Science Center
UM-HET3maleAcarbose1000 ppm480 daysPMID 27312235 2016med 793 max 12852012University of Texas Health Science Center
UM-HET3maleControl PMID 30688027 2019med 758 max 12602012University of Texas Health Science Center
UM-HET3male2-(2-Hydroxyphenyl)benzoxazole1 ppm450 daysPMID 30688027 2019med 741 max 11212012University of Texas Health Science Center

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:
  • What are the longest and shortest living strains of mice?
  • How does temperature affect the lifespan of worms?
  • Which strain of rats lives the same long on different diets?
  • Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
  • Which husbandry conditions produce the longest lifespan in certain species?

[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.