ALEC mice - Animal Life Expectancy Comparisons in Mice

Range limit to

486 cohorts selected out of 486 total, 829 median lifespan -

Strain	Sex	Treatment	Dosage	Temperature	Density	Start age	Study	Lifespan	Year	Site	Overmortality

UM-HET3	female	4-OH-PBN	315 ppm	21°C - 23°C	4	120 days	PMID 18631321 2009	med 876 max 1119	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	Acarbose	1000 ppm			480 days	PMID 27312235 2016	med 919 max 1243	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	Aspirin	20 ppm	21°C - 23°C	4	120 days	PMID 18631321 2009	med 844 max 1163	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	Control					PMID 30688027 2019	med 877 max 1255	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	Control		21°C - 23°C	4		PMID 18631321 2009	med 860 max 1212	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	2-(2-Hydroxyphenyl)benzoxazole	1 ppm			450 days	PMID 30688027 2019	med 852 max 1226	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	NDGA	2500 ppm	21°C - 23°C	4	270 days	PMID 18631321 2009	med 893 max 1169	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	INT-767 FXR/TGR5 agonist	180 ppm			300 days	PMID 30688027 2019	med 856 max 1172	2012	University of Texas Health Science Center	Calculate	Plot

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:

What are the longest and shortest living strains of mice?
How does temperature affect the lifespan of worms?
Which strain of rats lives the same long on different diets?
Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
Which husbandry conditions produce the longest lifespan in certain species?

References:
[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.