ALEC mice - Animal Life Expectancy Comparisons in Mice

Range limit to

486 cohorts selected out of 486 total, 829 median lifespan -

Strain	Sex	Treatment	Dosage	Temperature	Density	Start age	Study	Lifespan	Year	Site	Overmortality

C57BL/6J	female	Syringaresinol	300 ppm			150 days	PMID 36179270 2022	med 582 max 1250	2021		Calculate	Plot
C57BL/6J	male						PMID 34666007 2022	med 631 max 1252	2021		Calculate	Plot
UM-HET3	female	4-OH-PBN	315 ppm	21°C - 23°C	4	120 days	PMID 18631321 2009	med 876 max 1119	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	Aspirin	20 ppm	21°C - 23°C	4	120 days	PMID 18631321 2009	med 844 max 1163	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	Control		21°C - 23°C	4		PMID 18631321 2009	med 860 max 1212	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	NDGA	2500 ppm	21°C - 23°C	4	270 days	PMID 18631321 2009	med 893 max 1169	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	NFP	200 ppm	21°C - 23°C	4	120 days	PMID 18631321 2009	med 900 max 1144	2004	The Jackson Laboratory	Calculate	Plot
UM-HET3	male	4-OH-PBN	315 ppm	21°C - 23°C	3	120 days	PMID 18631321 2009	med 713 max 1077	2004	The Jackson Laboratory	Calculate	Plot

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:

What are the longest and shortest living strains of mice?
How does temperature affect the lifespan of worms?
Which strain of rats lives the same long on different diets?
Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
Which husbandry conditions produce the longest lifespan in certain species?

References:
[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.