ALEC mice - Animal Life Expectancy Comparisons in Mice

Range limit to

486 cohorts selected out of 486 total, 829 median lifespan -

Strain	Sex	Treatment	Dosage	Start age	Study	Lifespan	Year	Site	Overmortality

UM-HET3	male	17-a-estradiol	14.4 ppm	610 days	PMID 33788371 2021	med 800 max 1214	2016	The Jackson Laboratory	Calculate	Plot
UM-HET3	male	17-a-estradiol	14.4 ppm	610 days	PMID 33788371 2021	med 908 max 1147	2016	University of Michigan at Ann Arbor	Calculate	Plot
UM-HET3	male	17-a-estradiol	14.4 ppm	610 days	PMID 33788371 2021	med 801 max 1188	2016	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	Rapamycin	14 ppm	600 days	PMID 19587680 2009	med 1014 max 1360	2005	The Jackson Laboratory	Calculate	Plot
UM-HET3	male	Rapamycin	14 ppm	600 days	PMID 19587680 2009	med 819 max 1196	2005	The Jackson Laboratory	Calculate	Plot
UM-HET3	female	Rapamycin	14 ppm	600 days	PMID 19587680 2009	med 1036 max 1274	2005	University of Michigan at Ann Arbor	Calculate	Plot
UM-HET3	male	Rapamycin	14 ppm	600 days	PMID 19587680 2009	med 1054 max 1254	2005	University of Michigan at Ann Arbor	Calculate	Plot
UM-HET3	female	Rapamycin	14 ppm	600 days	PMID 19587680 2009	med 975 max 1272	2005	University of Texas Health Science Center	Calculate	Plot

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:

What are the longest and shortest living strains of mice?
How does temperature affect the lifespan of worms?
Which strain of rats lives the same long on different diets?
Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
Which husbandry conditions produce the longest lifespan in certain species?

References:
[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.