Range limit to
486 cohorts selected out of 486 total, 829 median lifespan -
StrainSexTreatmentDosageTemperatureDensityStart ageStudyLifespanYearSite
UM-HET3maleINT-767 FXR/TGR5 agonist180 ppm300 daysPMID 30688027 2019med 900 max 12192012University of Michigan at Ann Arbor
UM-HET3maleAcarbose1000 ppm480 daysPMID 27312235 2016med 793 max 12852012University of Texas Health Science Center
UM-HET3male4-OH-PBN315 ppm21°C - 23°C3120 daysPMID 18631321 2009med 713 max 10772004The Jackson Laboratory
UM-HET3maleControl PMID 30688027 2019med 758 max 12602012University of Texas Health Science Center
UM-HET3maleAspirin20 ppm21°C - 23°C3120 daysPMID 18631321 2009med 846 max 12012004The Jackson Laboratory
UM-HET3male2-(2-Hydroxyphenyl)benzoxazole1 ppm450 daysPMID 30688027 2019med 741 max 11212012University of Texas Health Science Center
UM-HET3maleControl21°C - 23°C3 PMID 18631321 2009med 763 max 12162004The Jackson Laboratory
UM-HET3maleINT-767 FXR/TGR5 agonist180 ppm300 daysPMID 30688027 2019med 772 max 10612012University of Texas Health Science Center

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:
  • What are the longest and shortest living strains of mice?
  • How does temperature affect the lifespan of worms?
  • Which strain of rats lives the same long on different diets?
  • Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
  • Which husbandry conditions produce the longest lifespan in certain species?

[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.