ALEC mice - Animal Life Expectancy Comparisons in Mice

Range limit to

486 cohorts selected out of 486 total, 829 median lifespan -

Strain	Sex	Treatment	Dosage	Start age	Study	Lifespan	Year	Site	Overmortality

UM-HET3	female	Acarbose	1000 ppm	480 days	PMID 27312235 2016	med 919 max 1243	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	Control			PMID 30688027 2019	med 877 max 1255	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	2-(2-Hydroxyphenyl)benzoxazole	1 ppm	450 days	PMID 30688027 2019	med 852 max 1226	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	female	INT-767 FXR/TGR5 agonist	180 ppm	300 days	PMID 30688027 2019	med 856 max 1172	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	male	Acarbose	1000 ppm	480 days	PMID 27312235 2016	med 793 max 1285	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	male	Control			PMID 30688027 2019	med 758 max 1260	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	male	2-(2-Hydroxyphenyl)benzoxazole	1 ppm	450 days	PMID 30688027 2019	med 741 max 1121	2012	University of Texas Health Science Center	Calculate	Plot
UM-HET3	male	INT-767 FXR/TGR5 agonist	180 ppm	300 days	PMID 30688027 2019	med 772 max 1061	2012	University of Texas Health Science Center	Calculate	Plot

Lifespan: what is surprising?
This project is aimed at providing the answers to questions like:

What are the longest and shortest living strains of mice?
How does temperature affect the lifespan of worms?
Which strain of rats lives the same long on different diets?
Has there been any change in the lifespan of the same fly species with the same keeping conditions over time?
Which husbandry conditions produce the longest lifespan in certain species?

References:
[1] ITP: Intervention Testing in Mice
[2] ITP in worms
[3] DrugAge
[4] Lucanic M, et al. Pharmacological lifespan extension of invertebrates. doi: 10.1016/j.arr.2012.06.006.